For the best medical care in the United States, you should probably head to Minnesota. The Mayo Clinic, located in Rochester, tops the latest U.S. News rankings of the country’s best hospitals for children and adults. For the 27th annual list, U.S. News compared 5000 medical centers across the country, ranking them on their quality of general care as well as their expertise in 25 specialties.

The rankings are based on data pertaining to patient survival rates, number of patients, infection rates, staffing numbers, and other objective measures. Here are the top 20 hospitals in the general excellence rankings:

1. Mayo Clinic, Rochester, Minnesota
2. Cleveland Clinic
3. Massachusetts General Hospital, Boston
4. Johns Hopkins Hospital, Baltimore
5. UCLA Medical Center
6. New York-Presbyterian University Hospital of Columbia and Cornell
7. UCSF Medical Center, San Francisco
8. Northwestern Memorial Hospital, Chicago
9. Hospitals of the University of Pennsylvania-Penn Presbyterian, Philadelphia
10. NYU Langone Medical Center
11. Barnes-Jewish Hospital/Washington University, St. Louis
12. UPMC Presbyterian Shadyside, Pittsburgh
13. Brigham and Women’s Hospital, Boston
14. Stanford Health Care-Stanford Hospital, Stanford, California
15. Mount Sinai Hospital, New York
16. Duke University Hospital, Durham, North Carolina
17. Cedars-Sinai Medical Center, Los Angeles
18. University of Michigan Hospitals and Health Centers, Ann Arbor
19. Houston Methodist Hospital
20. University of Colorado Hospital, Aurora